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Toward the end of 2019, Marone said, Friedmann started telling him, “The end is near.” Sometimes he’d say it in Latin. Growing more concerned, Marone asked Friedmann, “What’s going on with you? Are you thinking about doing something?”，这一点在电影中也有详细论述
This reaction would contain only low concentrations of the dNTPs and relied upon brief incubation times, so that DNA synthesis would stall at random positions along the template and yield a population of DNA fragments with varying lengths. These unfinished DNA fragments were then purified and used as templates in four “minus” and four “plus” reactions.
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